



N°01 Five Peptide Serum
Beautiful skin is built.
N°01 combines 5 advanced peptides and 3 botanical actives in a weightless, milky serum that supports collagen, strengthens the skin barrier, and helps reveal firmer, healthier-looking skin with consistent use. 30 ml.
Suitable For
Designed for every skin type, especially skin experiencing dryness, dehydration, or the visible signs of aging.
pH range: 5.00-6.50
A pH gently aligned with your skin's own natural balance.
How to use
Apply three to four drops to clean, slightly damp skin, morning and evening. Press gently into face and neck, let it absorb, then follow with moisturizer. Consistency matters more than quantity.
Ingredients
Full INCI List
Aqua (Water), Glycerin (Vegetable), Aloe Barbadensis Leaf Juice, Sodium Hyaluronate (Hyaluronic Acid), Salvia Hispanica (Chia) Seed Extract, Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Hexapeptide-9, Punica Granatum (Pomegranate) Seed Oil, Opuntia Tuna (Prickly Pear) Flower/Stem Extract, Proline, PCA, Sodium PCA, Isoleucine, Histidine, Threonine, Glycine, Sodium Lactate, Phenylalanine, Arginine, Aspartic Acid, Alanine, Serine, Valine, Carrageenan, Palmitoyl Pentapeptide-4, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Sodium Hydroxide, Hydroxyethylcellulose, Citric Acid, Sodium Benzoate, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate, Polysorbate 20, Fragrance, Iso E Super, Linalool, Linalyl Acetate, Benzyl Salicylate, Coumarin, Limonene, Geraniol.
A considered 6–8 week ritual, morning and evening.
Most people notice smoother, more hydrated skin within 2 weeks.
Every batch tested and traceable. Manufactured in an ISO 22716-certified facility.

Vegan

Cruelty-Free

Paraben-Free

Sulfate-Free

Phthalate-Free

30-Day Skin Promise
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Here. You are building something.
Healthy skin begins with intelligent formulation. Nº01 is built on 5 peptides, each chosen for a distinct role, working together to support the skin's own collagen architecture, protect what's already there, and improve the communication between cells that keeps skin firm, smooth, and resilient over time. Structural, not corrective.
Around them sits a base that does real work: low-molecular-weight hyaluronic acid for multi-layer hydration, chia seed extract and pomegranate seed oil for barrier support and antioxidant protection, prickly pear flower extract, and a full complex of amino acids, the skin's own natural moisturizing factors. The texture is light and milky, absorbing in seconds and leaving skin soft rather than coated.
Benefits
- Supports the skin's natural collagen production, for visibly firmer, more resilient skin over time
- Strengthens the skin barrier, helping skin retain moisture and better resist daily stress
- Delivers multi-layer hydration for a plumper, more comfortable complexion, morning and evening
- Improves the appearance of fine lines and uneven texture, for a smoother, more refined finish
- Reinforces cell-to-cell communication, supporting long-term skin elasticity and structural integrity
Five Peptides
Rather than relying on a single pathway, Nº01 supports the skin through multiple mechanisms: signaling new collagen, protecting what's already there, and reinforcing structural integrity.
- Palmitoyl Pentapeptide-4 · The most extensively studied peptide in skincare. Signals fibroblasts to produce collagen, elastin, and hyaluronic acid.
- Tripeptide-1 · Supports collagen renewal through the TGF-beta pathway.
- Palmitoyl Tetrapeptide-7 · Helps protect existing collagen from low-grade inflammation.
- Palmitoyl Tripeptide-5 · Stimulates collagen while helping limit the enzymes that break it down.
- Hexapeptide-9 · Strengthens cell-to-matrix communication and epidermal cohesion.
Hydration & Botanical Complex
- Chia Seed Extract · Omega-3 rich. Barrier support and calm.
- Pomegranate Seed Oil · Punicic acid. Antioxidant defence.
- Prickly Pear Flower Extract · Soothing, water-retaining.
- Sodium Hyaluronate · Low-molecular-weight hyaluronic acid that draws and holds water at multiple skin depths for lasting, plump hydration.
- Amino Acid Complex (Proline, Glycine, Arginine, Serine & more) · The same amino acids and humectants your skin produces naturally to hold moisture, replenished here to reinforce your skin's own hydration system.

From Our Founder
When people compliment my skin today, they often assume it's genetics.
The truth is much simpler.
As a teenager, I struggled with oily, acne prone skin and spent years chasing quick fixes. Over time, I learned that healthy skin is built through consistency, patience, and caring for it every single day.
As life took me from Brazil to Ireland, Madrid, and Barcelona, one ritual never changed. Taking a few quiet moments to care for my skin became an act of self respect and a source of confidence before stepping into the world.
That belief became Soul Perla.
Nº01 was the first product I created to put that belief into practice: 3–4 drops, morning and evening, the same small ritual I still follow every day.
Nº01 Five Peptide Serum was created with intention, blending advanced skin science with carefully selected botanical ingredients to support collagen, strengthen the skin barrier, and help build healthier, more resilient skin over time.
I believe that when you care for yourself first, you show up differently. You feel more confident, more present, and more ready to build the life you want.
I hope Soul Perla becomes part of your story, just as skincare has always been part of mine.
Your Soul Perla moment begins now.
With love,
Jéssica Cavalcante
Founder, Soul Perla
Loved by Women Who Live with Intention
"I had heard so many great things about peptides, but I had never tried a formula with five advanced peptides before. N°01 completely changed my mind! Now I understand the hype. This serum has exceeded my expectations. My skin feels firmer, smoother, more hydrated, and has a beautiful, healthy glow. As a woman over 40, I highly recommend N°01 to anyone looking for an effective addition to their skincare routine. I couldn’t be happier with the results!"
- Aline Z.
"When I first picked up the N°01 Five Peptide Serum, I’ll admit I expected just another pretty serum full of promises. But it truly exceeded my expectations. From the very first application, I noticed my skin felt softer and looked fresher..."
- Ana O.
"...The serum's lightweight texture absorbs beautifully, and its fresh, elegant fragrance makes every application feel like a luxurious experience.
This is a high-quality product that fits perfectly into an everyday skincare routine. If you are looking for brighter, healthier-looking skin, I highly recommend giving it a try!"
- Gabriella
Need help?
Frequently Asked Questions
About Soul Perla Nº1
Most people notice smoother, more hydrated skin within the first 2 weeks. Firmer, healthier-looking skin takes more time. Because peptides support your skin's natural collagen production, we recommend consistent use for 4–8 weeks to experience the full benefits. Beautiful skin is built over time.
Soul Perla Nº1 is suitable for all skin types, including dry, oily, combination, and mature skin. Its lightweight texture absorbs quickly without leaving a greasy finish.
There's no perfect age. Since collagen production naturally begins to decline in your mid-20s, peptides can help support healthy-looking skin both as a preventive step and as part of an age-supporting routine.
The formula is lightweight and designed to suit all skin types, including oily and blemish-prone skin. While individual skin can respond differently to any ingredient, the serum is formulated to absorb quickly without leaving a heavy residue.
Yes. Healthy skin isn't gender-specific. Soul Perla Nº1 is formulated for anyone looking to improve hydration, support collagen production, and maintain healthier-looking skin.
Soul Perla Nº1 combines five carefully selected peptides with hydrating, skin-supporting ingredients in a lightweight formula designed for daily use. Rather than relying on a single "hero" ingredient, the formula focuses on long-term skin health by supporting hydration, elasticity, and your skin's natural collagen production.
How to Use
Apply 3–4 drops to clean, slightly damp skin, morning and evening. Gently press the serum into your face and neck, then follow with your moisturizer. During the day, always finish with SPF.
Soul Perla Nº1 is formulated with aloe vera and sodium hyaluronate, ingredients that attract and retain moisture. Applying it to slightly damp skin helps maximize hydration and allows the serum to absorb more effectively.
Apply Soul Perla Nº1 after cleansing (and toner or essence, if you use one) and before moisturizer or facial oil. As a general rule, apply skincare from the lightest texture to the richest.
Soul Perla Nº1 has a lightweight, silky texture that absorbs quickly without feeling sticky or heavy. It layers beautifully under moisturizer, sunscreen, and makeup.
Yes. Allow the serum to absorb for about 30–60 seconds before applying moisturizer, sunscreen, or makeup. Its lightweight finish creates a smooth base without pilling.
Absolutely. The neck and décolleté are often among the first areas to show visible signs of aging. Apply the serum to your face, neck, and chest as part of your daily routine for more comprehensive care.
Pairing with Other Skincare
Yes. Soul Perla Nº1 pairs well with retinol. Many people prefer using the serum in the morning and retinol at night, but they can also be used in the same evening routine by applying the serum first. If you're new to retinol, introduce products gradually.
Absolutely. Soul Perla Nº1 works well alongside Vitamin C serums and can be used in the same routine without compromising performance.
Yes. If you're using strong exfoliating acids, we recommend alternating routines or applying them at different times of the day to help maintain a healthy skin barrier.
The formula contains no retinoids or salicylic acid. However, because every pregnancy is different, we recommend consulting your healthcare provider before introducing any new skincare product.
Formula & Ingredients
Soul Perla Nº1 is formulated with soothing, hydrating ingredients and is free from exfoliating acids, drying alcohols, and harsh actives. While it's gentle enough for daily use, every skin is unique. If you have sensitive or reactive skin, we recommend starting with once a day or every other day, then gradually increasing to twice daily as your skin becomes comfortable. It's also completely normal for your skin's sensitivity to change throughout the year. Weather, seasonal changes, stress, travel, hormonal fluctuations, or disruptions to your routine can all affect how your skin responds. If your skin feels more sensitive than usual, simply reduce the frequency until it feels comfortable again, then gradually return to your regular routine. At Soul Perla, we believe skincare should adapt to your life, not the other way around. The goal isn't perfection; it's consistency. Whether you're using the serum once a day or twice a day, consistency over time is far more important than frequency. We also recommend performing a patch test before your first use, especially if your skin is particularly sensitive.
Yes. Soul Perla Nº1 has a delicate floral scent that gently fades after application. All fragrance allergens are fully disclosed on the ingredient list.
Yes. Soul Perla Nº1 is 100% vegan, cruelty-free, and never tested on animals.
Soul Perla Nº1 is formulated without parabens, phthalates, sulfates, mineral oil, or silicones, allowing the focus to remain on effective, skin-loving ingredients.
Yes, slightly. Because we use botanical ingredients, natural variations in color or scent can occur from batch to batch. These differences are normal and do not affect the product's quality or performance.
Storage & Product Care
With twice-daily use of 3–4 drops, a 30 mL bottle typically lasts around 8 weeks, depending on the amount used.
Store the bottle in a cool, dry place away from direct sunlight and excessive heat. Always close the dropper securely after each use.
Quality & Transparency
A Certificate of Analysis (COA) is a quality document issued for each production batch. It confirms that the finished product met its required specifications before being released, including tests for appearance, pH, viscosity, and microbiological safety.
Yes. Simply email moment@soulperla.com with the batch number printed on your bottle, and we'll gladly provide the Certificate of Analysis for that specific batch.
Yes. Every production batch is tested against strict quality specifications before it is released. Only batches that meet all required standards are approved for sale.
Soul Perla, LLC is the Responsible Person for Soul Perla Nº1 under the Modernization of Cosmetics Regulation Act (MoCRA). We maintain the product's safety documentation, oversee quality compliance, and manage any consumer safety reports in accordance with U.S. regulations.
Yes. Soul Perla Nº1 is manufactured in a facility certified to ISO 22716, the internationally recognized Good Manufacturing Practices (GMP) standard for cosmetics. This certification reflects rigorous processes for hygiene, quality control, documentation, traceability, and manufacturing consistency.
ISO 22716 certification is assessed by an independent, accredited certification body, not by the manufacturer or by Soul Perla. The certification is maintained through regular audits to ensure the facility continues to meet internationally recognized Good Manufacturing Practices (GMP).
Soul Perla Nº1 is proudly manufactured in the United States in an ISO 22716-certified facility that follows internationally recognized Good Manufacturing Practices for cosmetics.
Yes. Every bottle carries a batch number that allows us to trace its production history, quality testing, and Certificate of Analysis. This level of traceability helps ensure transparency and quality control throughout the manufacturing process.
We recommend a patch test and consistent use for 4 to 8 weeks to give the formula time to work. If Nº01 still isn't the right fit, reach out to moment@soulperla.com within 30 days of delivery. We review these requests individually and will offer a suitable solution, such as guidance, a replacement, or a refund.
Scientific References
Peptides
- Robinson LR, Fitzgerald NC, Doughty DG, et al. "Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin." International Journal of Cosmetic Science, 2005.
Summary: A 12-week, double-blind, placebo-controlled, split-face study in 93 women aged 35–55, comparing a moisturizer containing 3 ppm Pal-KTTKS (Palmitoyl Pentapeptide-4) against the same moisturizer without it. Pal-KTTKS produced significant, well-tolerated improvement in wrinkles and fine lines versus placebo by both instrumental and expert-grader analysis.
Link: pubmed.ncbi.nlm.nih.gov/18492182 - Leroux R, Ringenbach C, Marchand T, et al. "A new matrikine-derived peptide up-regulates longevity genes..." International Journal of Cosmetic Science, 2020.
Summary: In human dermal fibroblast cultures, a palmitoylated tripeptide fragment increased collagen and fibronectin production and up-regulated FOXO and sestrin gene expression, both associated with cell longevity and matrix production.
Link: pubmed.ncbi.nlm.nih.gov/31596957 - Pharmaceuticals journal review, "Usage of Synthetic Peptides in Cosmetics for Sensitive Skin." Pharmaceuticals, 2021.
Summary: A peer-reviewed review covering Palmitoyl Tripeptide-5's ability to reduce matrix metalloproteinases (MMPs, the enzymes that break down collagen) while promoting Type I and Type II collagen synthesis, and Palmitoyl Tetrapeptide-7's role in decreasing IL-6 (an inflammatory marker) and reducing UVB-induced inflammation.
Link: pmc.ncbi.nlm.nih.gov/articles/PMC8400021 - Chang H, Tao K, Yang Y, et al. "Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging." Journal of Cosmetic Dermatology, 2025.
Summary: A randomized, double-blind, active- and vehicle-controlled 56-day clinical trial comparing 0.002% cyclized hexapeptide-9 serum against retinol and vehicle. The hexapeptide-9 formula produced significantly larger reductions in crow's-feet and forehead wrinkle number, area, and roughness than retinol for nearly every measured outcome.
Link: pubmed.ncbi.nlm.nih.gov/40586182
Hyaluronic Acid
- Snetkov P, Zakharova K, Morozkina S, et al. / general review: "Benefits of topical hyaluronic acid for skin quality and signs of skin aging." Journal of Cosmetic Dermatology (Dermatologic Therapy family), 2022.
Summary: Review noting that a randomized controlled trial in 65 women with periocular wrinkles found significant improvement in skin hydration and elasticity versus placebo after 60 days using 0.1% sodium hyaluronate formulations, with lower-molecular-weight HA showing greater wrinkle-depth reduction.
Link: pmc.ncbi.nlm.nih.gov/articles/PMC10078143 - "Efficacy Evaluation of a Topical Hyaluronic Acid Serum..." Dermatology and Therapy, 2021.
Summary: Clinical evaluation of a topical hyaluronic acid serum showing measurable improvements in skin hydration and smoothness.
Link: pmc.ncbi.nlm.nih.gov/articles/PMC8322246
Aloe Vera
- Umborowati MA, Anggraeni S, Damayanti, Prakoeswa CRS. "The beneficial effect of Aloe vera in skin barrier function improvement: a double-blind randomized trial of Madurese batik craftswomen." Journal of Pakistan Association of Dermatologists, 2022.
Summary: Double-blind randomized trial in an occupationally skin-stressed population, showing a significant decrease in transepidermal water loss (TEWL) and a significant increase in stratum corneum hydration at 2 and 4 weeks in the Aloe vera group.
Link: doi.org/10.66344/jpad.v32i1.1828 (also indexed at jpad.com.pk) - Laneri S, Di Lorenzo RM, Bernardi A, Sacchi A, Dini I. "Aloe barbadensis: A Plant of Nutricosmetic Interest." Natural Product Communications, 2020.
Summary: Review of Aloe barbadensis's dermatological actions, including moisturizing, anti-inflammatory, and wound-healing properties attributed to its polysaccharide and amino-acid content.
Link: journals.sagepub.com/doi/10.1177/1934578X20932744
Chia Seed Extract
- "HYVIA™: A novel, topical chia seed extract that improves skin hydration." Journal of Cosmetic Dermatology, 2020.
Summary: In vitro work showed a Vitamin-F-enriched chia seed extract increased keratinocyte hydration markers (aquaporin-3 and hyaluronic acid synthase-2); a 16-subject clinical trial with a 0.1% chia extract cream showed measurable improvement in skin hydration.
Link: doi.org/10.1111/jocd.13469
Pomegranate Seed Oil
- "Biochemical Pilot Study on Effects of Pomegranate Seed Oil Extract... on Neurologically Mediated Skin Inflammation." Molecules, 2023.
Summary: Pomegranate seed oil extract reduced markers of oxidative stress and inflammation (including collagenase and elastase activity) in animal and human skin models.
Link: pmc.ncbi.nlm.nih.gov/articles/PMC9865066 - "Punica granatum L. (Pomegranate) Extracts and Their Effects on Skin." Pharmaceutics, 2024.
Summary: Comprehensive review of pomegranate's antioxidant and photoprotective compounds, including punicic acid and ellagic acid, and their documented effects on skin oxidative stress.
Link: pmc.ncbi.nlm.nih.gov/articles/PMC11054180
Prickly Pear (Opuntia)
- Madrigal-Santillán E, Portillo-Reyes J, Madrigal-Bujaidar E, et al. "Opuntia spp. in Human Health: A Comprehensive Summary on Its Pharmacological, Therapeutic, and Preventive Effects." Plants, 2022.
Summary: Comprehensive review documenting that Opuntia ficus-indica extracts protect the epidermal barrier and keratinocyte function, increase expression of filaggrin and loricrin (both key skin-barrier proteins), and that the plant's mucilage functions physiologically to absorb and regulate water.
Link: pmc.ncbi.nlm.nih.gov/articles/PMC9505094
General Peptide & Collagen Science
- "Peptides: Emerging Candidates for the Prevention and Treatment of Skin Aging — A Review." Biomolecules, 2025.
Summary: Broad peer-reviewed review of cosmetic peptide categories (carrier, signal, enzyme-inhibitor, neurotransmitter-inhibitor peptides) and their documented roles in collagen stimulation, elasticity, and wrinkle reduction, including the Robinson 2005 KTTKS trial.
Link: pmc.ncbi.nlm.nih.gov/articles/PMC11762834

