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N°01 Five Peptide Serum

Sale price$59.00

Beautiful skin is built.

N°01 combines 5 advanced peptides and 3 botanical actives in a weightless, milky serum that supports collagen, strengthens the skin barrier, and helps reveal firmer, healthier-looking skin with consistent use. 30 ml.


Size:

A considered 6–8 week ritual, morning and evening.

Most people notice smoother, more hydrated skin within 2 weeks.

Every batch tested and traceable. Manufactured in an ISO 22716-certified facility.

Vegan

Cruelty-Free

Paraben-Free

Sulfate-Free

Phthalate-Free

30-Day Skin Promise

Soul Perla No.01 Five Peptide Serum in a frosted glass dropper bottle with a black cap and white label, set against a clean white background.
N°01 Five Peptide Serum Sale price$59.00

Here. You are building something.

Healthy skin begins with intelligent formulation. Nº01 is built on 5 peptides, each chosen for a distinct role, working together to support the skin's own collagen architecture, protect what's already there, and improve the communication between cells that keeps skin firm, smooth, and resilient over time. Structural, not corrective.

Around them sits a base that does real work: low-molecular-weight hyaluronic acid for multi-layer hydration, chia seed extract and pomegranate seed oil for barrier support and antioxidant protection, prickly pear flower extract, and a full complex of amino acids, the skin's own natural moisturizing factors. The texture is light and milky, absorbing in seconds and leaving skin soft rather than coated.

Benefits

  • Supports the skin's natural collagen production, for visibly firmer, more resilient skin over time
  • Strengthens the skin barrier, helping skin retain moisture and better resist daily stress
  • Delivers multi-layer hydration for a plumper, more comfortable complexion, morning and evening
  • Improves the appearance of fine lines and uneven texture, for a smoother, more refined finish
  • Reinforces cell-to-cell communication, supporting long-term skin elasticity and structural integrity

Five Peptides

Rather than relying on a single pathway, Nº01 supports the skin through multiple mechanisms: signaling new collagen, protecting what's already there, and reinforcing structural integrity.

  • Palmitoyl Pentapeptide-4 · The most extensively studied peptide in skincare. Signals fibroblasts to produce collagen, elastin, and hyaluronic acid.
  • Tripeptide-1 · Supports collagen renewal through the TGF-beta pathway.
  • Palmitoyl Tetrapeptide-7 · Helps protect existing collagen from low-grade inflammation.
  • Palmitoyl Tripeptide-5 · Stimulates collagen while helping limit the enzymes that break it down.
  • Hexapeptide-9 · Strengthens cell-to-matrix communication and epidermal cohesion.

Hydration & Botanical Complex

  • Chia Seed Extract · Omega-3 rich. Barrier support and calm.
  • Pomegranate Seed Oil · Punicic acid. Antioxidant defence.
  • Prickly Pear Flower Extract · Soothing, water-retaining.
  • Sodium Hyaluronate · Low-molecular-weight hyaluronic acid that draws and holds water at multiple skin depths for lasting, plump hydration.
  • Amino Acid Complex (Proline, Glycine, Arginine, Serine & more) · The same amino acids and humectants your skin produces naturally to hold moisture, replenished here to reinforce your skin's own hydration system.

Loved by Women Who Live with Intention

"I had heard so many great things about peptides, but I had never tried a formula with five advanced peptides before. N°01 completely changed my mind! Now I understand the hype. This serum has exceeded my expectations. My skin feels firmer, smoother, more hydrated, and has a beautiful, healthy glow. As a woman over 40, I highly recommend N°01 to anyone looking for an effective addition to their skincare routine. I couldn’t be happier with the results!"
- Aline Z.

"When I first picked up the N°01 Five Peptide Serum, I’ll admit I expected just another pretty serum full of promises. But it truly exceeded my expectations. From the very first application, I noticed my skin felt softer and looked fresher..."
- Ana O.

"...The serum's lightweight texture absorbs beautifully, and its fresh, elegant fragrance makes every application feel like a luxurious experience.

This is a high-quality product that fits perfectly into an everyday skincare routine. If you are looking for brighter, healthier-looking skin, I highly recommend giving it a try!"
- Gabriella

Need help?

Frequently Asked Questions

About Soul Perla Nº1

How to Use

Pairing with Other Skincare

Formula & Ingredients

Storage & Product Care

Quality & Transparency

  • 5 stars: 9 (100%)
  • 4 stars: 0 (0%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
D
David K.

In the first week, I saw my wrinkles and crow's feet improve. They get better every day!

A
Amanda S.

This serum is my new holy grail! I have been using it for almost 2 weeks and I have seen a few visible improvements to my skin. My skin feels and looks smoother, and I am noticing a couple dark spots lightening up. Really excited to keep using it in my daily routine to see even more benefits! My only qualm about this product is the fragrance. It smells a tad like baby powder to me. There is added fragrance, which I definitely think the formula could do without in the future!

G
Gabriella

Number 01 Five Peptides Serum is amazing!

I've been passionate about skincare for many years and have tried many products from different brands. I can honestly say that the Number 01 Five Peptides Serum has become one of my favourites. It has helped my skin feel healthier, smoother, and perfectly prepped to get the most out of the rest of my skincare routine.

The serum's lightweight texture absorbs beautifully, and its fresh, elegant fragrance makes every application feel like a luxurious experience.

This is a high-quality product that fits perfectly into an everyday skincare routine. If you are looking for brighter, healthier-looking skin, I highly recommend giving it a try!

G
Glauber C.

First impression when I applied N.01 to my skin was the amazing fresh herbal scents, the smoothness and how it felt in the skin: just like silk! Been using it for a few days now and I definitely feel my skin more hydrated and smooth.. highly recommend this product!!

C
Carol G.

I've been loving the N°01 Five Peptide Serum by Soul Perla! Peptides are one of the biggest skincare trends right now, and this serum is a great way to add them to your routine. It's lightweight, absorbs quickly, and leaves my skin feeling hydrated, smoother, and looking more radiant. With consistent use, I've noticed my skin feels firmer and healthier. I definitely recommend it to anyone looking for an effective peptide serum that delivers visible results.

A
Aline Z.

I had heard so many great things about peptides, but I had never tried a formula with five advanced peptides before. N°01 completely changed my mind! Now I understand the hype. This serum has exceeded my expectations. My skin feels firmer, smoother, more hydrated, and has a beautiful, healthy glow. As a woman over 40, I highly recommend N°01 to anyone looking for an effective addition to their skincare routine. I couldn’t be happier with the results!

B
Bruna M.

I highly recommend the No.1 Five Peptide Serum and the entire experience behind SoulPerla. From the quality of the product to the care and attention that goes into the brand, everything exceeded my expectations. The serum feels amazing on my skin, and I’ve been really happy with the results. Without a doubt, I’ll be buying it again!

T
Táfili S.

I’ve been using this serum for a few days and I’m already loving it! The texture is incredibly lightweight, it spreads easily, and leaves my skin feeling hydrated without being greasy. I’ve noticed my skin looks softer, more radiant, and healthier. It also absorbs quickly and a little goes a long way. It’s definitely become part of my skincare routine, and I’ll be purchasing it again. Highly recommend!

A
Ana O.

When I first picked up the N°01 Five Peptide Serum, I’ll admit I expected just another pretty serum full of promises. But it truly exceeded my expectations. From the very first application, I noticed my skin felt softer and looked fresher. It has five peptides — which are basically active ingredients that help the skin stay firm and “rebuilt” over time — along with plant extracts like chia and pomegranate that hydrate and give the skin that healthy look. I don’t know anything about chemistry, but what matters is that you can actually feel the difference.

But what really won me over was the experience of using it: a light, silky texture that glides on, absorbs in seconds, and leaves the skin soft, with no heaviness or residue. And it delivers all of that while staying clean — vegan, cruelty-free, and free of parabens, sulfates, and phthalates. That combination of serious formulation and clean standards is exactly what exceeded my expectations.

Scientific References

Peptides

  1. Robinson LR, Fitzgerald NC, Doughty DG, et al. "Topical palmitoyl pentapeptide provides improvement in photoaged human facial skin." International Journal of Cosmetic Science, 2005.
    Summary: A 12-week, double-blind, placebo-controlled, split-face study in 93 women aged 35–55, comparing a moisturizer containing 3 ppm Pal-KTTKS (Palmitoyl Pentapeptide-4) against the same moisturizer without it. Pal-KTTKS produced significant, well-tolerated improvement in wrinkles and fine lines versus placebo by both instrumental and expert-grader analysis.
    Link: pubmed.ncbi.nlm.nih.gov/18492182
  2. Leroux R, Ringenbach C, Marchand T, et al. "A new matrikine-derived peptide up-regulates longevity genes..." International Journal of Cosmetic Science, 2020.
    Summary: In human dermal fibroblast cultures, a palmitoylated tripeptide fragment increased collagen and fibronectin production and up-regulated FOXO and sestrin gene expression, both associated with cell longevity and matrix production.
    Link: pubmed.ncbi.nlm.nih.gov/31596957
  3. Pharmaceuticals journal review, "Usage of Synthetic Peptides in Cosmetics for Sensitive Skin." Pharmaceuticals, 2021.
    Summary: A peer-reviewed review covering Palmitoyl Tripeptide-5's ability to reduce matrix metalloproteinases (MMPs, the enzymes that break down collagen) while promoting Type I and Type II collagen synthesis, and Palmitoyl Tetrapeptide-7's role in decreasing IL-6 (an inflammatory marker) and reducing UVB-induced inflammation.
    Link: pmc.ncbi.nlm.nih.gov/articles/PMC8400021
  4. Chang H, Tao K, Yang Y, et al. "Novel Cyclized Hexapeptide-9 Outperforms Retinol Against Skin Aging." Journal of Cosmetic Dermatology, 2025.
    Summary: A randomized, double-blind, active- and vehicle-controlled 56-day clinical trial comparing 0.002% cyclized hexapeptide-9 serum against retinol and vehicle. The hexapeptide-9 formula produced significantly larger reductions in crow's-feet and forehead wrinkle number, area, and roughness than retinol for nearly every measured outcome.
    Link: pubmed.ncbi.nlm.nih.gov/40586182

Hyaluronic Acid

  1. Snetkov P, Zakharova K, Morozkina S, et al. / general review: "Benefits of topical hyaluronic acid for skin quality and signs of skin aging." Journal of Cosmetic Dermatology (Dermatologic Therapy family), 2022.
    Summary: Review noting that a randomized controlled trial in 65 women with periocular wrinkles found significant improvement in skin hydration and elasticity versus placebo after 60 days using 0.1% sodium hyaluronate formulations, with lower-molecular-weight HA showing greater wrinkle-depth reduction.
    Link: pmc.ncbi.nlm.nih.gov/articles/PMC10078143
  2. "Efficacy Evaluation of a Topical Hyaluronic Acid Serum..." Dermatology and Therapy, 2021.
    Summary: Clinical evaluation of a topical hyaluronic acid serum showing measurable improvements in skin hydration and smoothness.
    Link: pmc.ncbi.nlm.nih.gov/articles/PMC8322246

Aloe Vera

  1. Umborowati MA, Anggraeni S, Damayanti, Prakoeswa CRS. "The beneficial effect of Aloe vera in skin barrier function improvement: a double-blind randomized trial of Madurese batik craftswomen." Journal of Pakistan Association of Dermatologists, 2022.
    Summary: Double-blind randomized trial in an occupationally skin-stressed population, showing a significant decrease in transepidermal water loss (TEWL) and a significant increase in stratum corneum hydration at 2 and 4 weeks in the Aloe vera group.
    Link: doi.org/10.66344/jpad.v32i1.1828 (also indexed at jpad.com.pk)
  2. Laneri S, Di Lorenzo RM, Bernardi A, Sacchi A, Dini I. "Aloe barbadensis: A Plant of Nutricosmetic Interest." Natural Product Communications, 2020.
    Summary: Review of Aloe barbadensis's dermatological actions, including moisturizing, anti-inflammatory, and wound-healing properties attributed to its polysaccharide and amino-acid content.
    Link: journals.sagepub.com/doi/10.1177/1934578X20932744

Chia Seed Extract

  1. "HYVIA™: A novel, topical chia seed extract that improves skin hydration." Journal of Cosmetic Dermatology, 2020.
    Summary: In vitro work showed a Vitamin-F-enriched chia seed extract increased keratinocyte hydration markers (aquaporin-3 and hyaluronic acid synthase-2); a 16-subject clinical trial with a 0.1% chia extract cream showed measurable improvement in skin hydration.
    Link: doi.org/10.1111/jocd.13469

Pomegranate Seed Oil

  1. "Biochemical Pilot Study on Effects of Pomegranate Seed Oil Extract... on Neurologically Mediated Skin Inflammation." Molecules, 2023.
    Summary: Pomegranate seed oil extract reduced markers of oxidative stress and inflammation (including collagenase and elastase activity) in animal and human skin models.
    Link: pmc.ncbi.nlm.nih.gov/articles/PMC9865066
  2. "Punica granatum L. (Pomegranate) Extracts and Their Effects on Skin." Pharmaceutics, 2024.
    Summary: Comprehensive review of pomegranate's antioxidant and photoprotective compounds, including punicic acid and ellagic acid, and their documented effects on skin oxidative stress.
    Link: pmc.ncbi.nlm.nih.gov/articles/PMC11054180

Prickly Pear (Opuntia)

  1. Madrigal-Santillán E, Portillo-Reyes J, Madrigal-Bujaidar E, et al. "Opuntia spp. in Human Health: A Comprehensive Summary on Its Pharmacological, Therapeutic, and Preventive Effects." Plants, 2022.
    Summary: Comprehensive review documenting that Opuntia ficus-indica extracts protect the epidermal barrier and keratinocyte function, increase expression of filaggrin and loricrin (both key skin-barrier proteins), and that the plant's mucilage functions physiologically to absorb and regulate water.
    Link: pmc.ncbi.nlm.nih.gov/articles/PMC9505094

General Peptide & Collagen Science

  1. "Peptides: Emerging Candidates for the Prevention and Treatment of Skin Aging — A Review." Biomolecules, 2025.
    Summary: Broad peer-reviewed review of cosmetic peptide categories (carrier, signal, enzyme-inhibitor, neurotransmitter-inhibitor peptides) and their documented roles in collagen stimulation, elasticity, and wrinkle reduction, including the Robinson 2005 KTTKS trial.
    Link: pmc.ncbi.nlm.nih.gov/articles/PMC11762834